RANOPs and RHiNO

RANOPS – Respiratory and Neurological Outcomes in PreTerm Children

We plan to take a group of children aged 7-12 who were born at 34 weeks or less and already identified as having some breathing issues. This is a population-based questionnaire surveying preterm- and term-born children in Wales with >7000 returns. The survey assessed the respiratory and neurodevelopmental outcomes of preterm children with matched term-born children. This is by far the largest study of preterm-born children in the world. The data is currently being analysed and will be submitted for publication over the next few months.

http://www.bbc.co.uk/news/uk-wales-21580139

http://medicine.cf.ac.uk/news/health-premature-babies/

http://www.walesonline.co.uk/news/health-news/2013/02/18/new-study-aim-to-check-on-relative-health-of-premature-babies-as-they-grow-up-91466-32826830/

RHiNO – Respiratory Health Outcomes in Neonates

RHiNO is based on the RANOPs study with a view to recruiting children who responded to the RANOPs study. More than >97% of parents have indicated their willingness to join any future studies.

(a) obtaining DNA from >3000 preterm-born children for genomic studies,

(b) assessing 1,000 preterm-born children for airway obstruction, growth, etc.,

(d) instituting treatment;

(e) reassessing mechanisms; and

(f) assessing lung growth using state-of-the-art MRI using hyperpolarised 3He

This is a collaboration between the Universities of Cardiff, Bristol, Sheffield, Bangor (NWORTH) and University of South Wales:

Professor Sailesh Kotecha	Cardiff University
Professor John Henderson	University of Bristol
Professor James Wild	University of Sheffield
Dr Mark Williams	University of South Wales
Dr Julian Marchesi	Cardiff University
Dr Iolo Doull	Cardiff & Vale University Health Board
Dr Zoe Hoare	Bangor University
Kirstie Pye	Bangor University
Natalie Grice	Parent Representative
Dr John Lowe	Cardiff University
Dr Sarah Kotecha	Cardiff University