2025: Additional publications published from the RHiNO data jointly by Dr John Watkins and by Dr Chris Course studying the effects of pollution on the preterm lung and by Dr Michael Cousins together with teams from Budapest, Hungary and Brisbane, Australia on intra-breath mechanics of the newly defined phenotypes of pematurty-associated lung disease (PLD):
Course CW, Lewis PA, Kotecha SJ, Cousins M, Hart K, Heesom KJ, Watkins WJ, Kotecha S. Similarities of metabolomic disturbances in prematurity-associated obstructive lung disease to chronic obstructive pulmonary disease. Sci Reports 2024;14:23294. https://doi.org/10.1038/s41598-024-73704-1
Cousins M, Hart K, Radics B, Henderson AH, Hantos Z, Sly PD, Kotecha S. Intra-breath respiratory mechanics of phenotypes of prematurity-associated lung disease in school-aged children? Eur J Respir Open 2025 11(2): 00840-2024
July 2024: Additional papers have been published to try to understand the nature of the lung disease that children born prematurely can get – these are shown on the publications page – click here.
The data from the clinical trial in RHiNO was published in 2022 showing that a combination of inhaled corticosteroids and long acting beta2 agonists (ICS/LABA) combination improved the children’s lung function by 15% on average. The findings were published in JAMA Pediatrics in 2022: